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  1. Fujiya M, Ueno N, Kashima S, Tanaka K, Sakatani A, Ando K, Moriichi K, Konishi H, Kamiyama N, Tasaki Y, Omura T, Matsubara K,  Taruishi M, Okumura T. Long‐chain polyphosphate is a potential agent for inducing mucosal healing of the colon in ulcerative colitis. Clin Pharmacol Ther. 2019 Sep 12. doi: 10.1002/cpt.1628.

  2. Segawa S, Fujiya M (correspondence), Konishi H, Ueno N, Kobayashi N, Shigyo T, Kohgo Y. Probiotic-derived polyphosphate enhances the epithelial barrier function and maintains intestinal homeostasis through integrin-p38 MAPK pathwayPloS One 6 (8): e23278, 2011.

  3. Kashima S, Fujiya M (correspondence), Konishi H, Ueno N, Inaba Y, Moriichi K, Tanabe H, Ikuta K, Ohtake T, Kohgo Y. Polyphosphate, an active molecule derived from probiotic Lactobacillus brevis, improves the fibrosis in murine colitisTranslational Research 166(2):163-175, 2015.

  4. Tanaka K, Fujiya M (correspondence), Konishi H, Ueno N, Sasajima J, Moriichi K, Ikuta K, Tanabe H, Kohgo Y. Probiotic-derived polyphosphate improves the intestinal barrier function through the caveolin-dependent endocytic pathwayBiochemical and Biophysical Research Communications 27;467(4):847-52, 2015.

  5. Sakatani A, Fujiya M (correspondence), Ueno N, Kashima S, Sasajima J, Moriichi K, Ikuta K, Tanabe H, Kohgo Y. Lactobacillus brevis-derived polyphosphate inhibits colon cancer progression through the induction of cell apoptosisAnticancer Res 36(2):591-8, 2016.

  6. Ueno N, Fujiya M (correspondence), Segawa S, Nata T, Moriichi K, Tanabe H, Mizukami Y, Kobayashi N, Ito K, Kohgo Y. Heat-killed body of Lactobacillus brevis SBC8803 ameliorates intestinal injury in a murine model of colitis by enhancing the intestinal barrier functionInflammatory Bowel Diseases 17(11):2235-50, 2011.

  7. Fujiya M, Musch WM, Nakagawa Y, Hu S, Alverdy J, Kohgo Y, Schneewind O, Jabri B, Chang EB. The Bacillus subtilis quorum sensing molecule, CSF, contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter. Cell Host and Microbe 1 (4): 299-308, 2007.

  8. Okamoto K, Fujiya M (correspondence), Nata T, Ueno N, Inaba Y, Ishikawa C, Ito T, Moriichi K, Tanabe H, Mizukami Y, Chang EB, Kohgo Y. Competence and sporulation factor derived from Bacillus subtilis improves epithelial cell injury in intestinal inflammation via immunomodulation and cytoprotectionInt J Colorectal Diseases 27(8):1039-46, 2012.

  9. Fujiya M, Ueno N, Kohgo Y. Probiotic treatments for induction and maintenance of remission in inflammatory bowel diseases: A meta-analysis of randomized controlled trialsClin J Gastroenterol 7(1):1–13, 2014.

  10. Fujiya M, Kohgo Y. Novel perspectives in probiotic treatment: The efficacy and unveiled mechanisms of the physiological functions. Clin J Gastroenterol 3:117–127, 2010. (Review)

  11. Konishi H, Fujiya M (correspondence), Kohgo Y. Host-Microbe Interactions via Membrane Transport Systems. Environ Microbiol 17(4):931-7, 2015.

  12. Inaba Y, Ueno N, Numata M, Zhu X, Messer JS, Boone DL, Fujiya M, Kohgo Y, Musch MW, Chang EB. Soluble bioactive microbial mediators regulate proteasomal degradation and autophagy to protect against inflammation-induced stress. Am J Physiol Gastrointest Liver Physiol 311(4):G634-G647, 2016.

  13. Ueno N, Hasebe T, Kaneko A, Yamamoto M, Wang Y, Fujiya M, Kohgo Y, Kono T, Musch MW, Chang EB. TU-100 (Daikenchuto) and Ginger Ameliorate Anti-CD3 Antibody Induced T Cell-Mediated Murine Enteritis: Microbe-Independent Effects Involving Akt and NF-κB SuppressionPloS One 23;9(5):e97456, 2014.

  14. Konishi H, Fujiya M (correspondence), Kohgo Y. Traffic control of bacteria-derived molecules- A new system of host-bacterial crosstalkInternational Journal of Cell Biology 2013: 8 pages, 2013.

  15. Wakita Y, Shimizu C, Nakakita Y, Kaneda H, Kanda H, Segawa S, Shigyou T, Ohtake T, Fujiya M, Kohgo Y. Effect of Lactobacillus brevis SBC8803 on Gamma-Glutamyl Transferase in Japanese Habitual Drinkers: A Double-Blind, Placebo-Controlled StudyFood and Nutrition Sciences 3(5):678-684, 2012.



  1. Konishi H, Fujiya M (correspondence, equal contributor), Tanaka H, Ueno N, Moriichi K, Sasajima J, Ikuta K, Akutsu H, Tanabe H, Kohgo Y. Probiotic-derived ferrichrome inhibits colon cancer progression via JNK mediated apoptosis. Nature Communications 7:12365, 2016.

  2. Ijiri M, Fujiya M (equal contribution, correspondence), Konishi H, Tanaka H, Ueno N, Kashima S, Moriichi K, Sasajima J, Ikuta K, Okumura T. Ferrichrome identified from Lactobacillus casei ATCC334 induces apoptosis through its iron binding site in gastric cancer cells. Tumor Biology 39(6): 1010428317711311, 2017.



Inflammatory Bowel Disease

  1. Ando K, Fujiya M (equal contribution, correspondence), Nomura Y, Inaba Y, Sugiyama Y, Iwama T, Ijiri M, Takahashi K, Tanaka K, Sakatani A, Ueno N, Kashima S, Moriichi K, Mizukami Y, Okumura T. The incidence and risk factors of venous thromboembolism in Japanese inpatients with inflammatory bowel disease: A retrospective cohort study. Intest Res 16(3): 416-425, 2018.

  2. Nomura Y, Moriichi K, Fujiya M, Okumura T. The endoscopic findings of the upper gastrointestinal tract in patients with Crohn's disease. Clin J Gastroenterol 10(4):289-296, 2017.

  3. Iwama T, Sakatani A, Fujiya M (correspondence), Tanaka K, Fujibayashi S, Nomura Y, Ueno N, Kashima S, Gotoh T, Sasajima J, Moriichi K, Ikuta K. Increased dosage of infliximab is a potential cause of Pneumocystis carinii pneumoniaGut Pathogens 8:2, 2016.

  4. Hasebe T, Ueno N, Musch WM, Nadimpalli A, Kaneko A, Kaifuchi N, Watanabe J, Yamamoto M, Inaba Y, Kono T, Fujiya M, Kohgo Y, Chang EB. Daikenchuto (TU-100) shapes gut microbiota architecture and increases the production of ginsenoside metabolite compound KPharmacology Research & Perspectives 4(1):e00215, 2016.

  5. Moriichi K, Fujiya M (correspondence), Ijiri M, Tanaka K, Sakatani A, Dokoshi T, Fujibayashi S, Ando K, Nomura Y, Ueno N, Kashima S, Gotoh T, Sasajima J, Inaba Y, Ito T, Tanabe H, Saitoh Y, Kohgo Y. Quantification of autofluorescence imaging can accurately and objectively assess the severity of ulcerative colitis. International Journal of Colorectal Diseases 30(12):1639-43, 2015.

  6. Fujiya M, Sakatani A, Dokoshi T, Tanaka K, Ando K, Ueno N, Gotoh T, Kashima S, Tominaga M, Inaba Y, Ito T, Moriichi K, Tanabe H, Ikuta K, Ohtake T, Yokota K, Watari J, Saitoh Y, Kohgo Y. A bamboo joint-like appearance is a characteristic finding in the upper GIT of Crohn’s disease patients: A case-control studyMedicine (Baltimore), 94(37):e1500, 2015.

  7. Ando K, Fujiya M (correspondence), Konishi H, Ueno N, Inaba Y, Moriichi K, Ikuta K, Tanabe H, Ohtake T, Kohgo Y. Heterogeneous nuclear ribonucleoprotein A1 improves the intestinal injury by regulating apoptosis via trefoil factor 2 in mice with anti-CD3-induced enteritisInflammatory Bowel Diseases 21(7):1541-52, 2015.

  8. Sakatani A, Fujiya M (correspondence), Ito T, Inaba Y, Ueno N, Kashima S, Tominaga M, Moriichi K, Okamoto K, Tanabe H, Ikuta K, Ohtake T, Kono T, Furukawa H, Ashida T, Kohgo Y. Infliximab extends the duration until the first surgery in patients with Crohn’s diseaseBiomed Research International 2013:879491, 2013.

  9. Fujiya M, Inaba Y, Musch MW, Hu S, Kohgo Y, Chang EB. Cytokine Regulation of OCTN2 Expression and Activity in Small and Large IntestineInflammatory Bowel Diseases 17(4):907-16, 2011.

  10. Inaba Y, Ashida T, Ito T, Ishikawa C, Tanabe H, Maemoto A, Watari J, Ayabe T, Mizukami Y, Fujiya M (correspondence), Kohgo Y. The expression of the anti-microbial peptide α-defensin/cryptdins in intestinal crypts decreases at the initial phase of intestinal inflammation in a model of inflammatory bowel disease, IL-10 deficient miceInflammatory Bowel Diseases 16(9): 1488-95, 2010.

  11. Hu S, Ciancio MJ, Lahav M, Fujiya M, Lichtenstein L, Anant S, Musch MW, Chang EB. Translational Inhibition of Colonic Epithelial Heat Shock Proteins by IFN-γ and TNF-α in Intestinal Inflammation. Gastroenterology 133 (6); 1893-1904, 2007. 

  12. Fujiya M, Saitoh Y, Watari J, Moriichi K, Kohgo Y. Auto-Fluorescence Imaging is useful to assess the activity of ulcerative colitis. Digestive Endoscopy 19: 145-149, 2007.

  13. Fujiya M, Saitoh Y, Nomura M, Maemoto A, Fujiya K, Watari J, Ashida T, Ayabe T, Obara T, and Kohgo Y. Minute findings by magnifying colonoscopy are useful for the evaluation of ulcerative colitis. Gastrointest Endosc 56 (4); 535-542, 2002.

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